8. Application: Voice Preservation in Laryngeal Cancer

8.1 Clinical Context

Laryngeal cancer treatment often requires total laryngectomy — the surgical removal of the larynx. This eliminates

the patient’s natural voice. Post-surgery, patients develop alternative voice production methods, most commonly

tracheoesophageal puncture (TEP) speech, which uses a prosthesis to divert pulmonary air into the esophagus for

phonation [9].

Current voice banking approaches record the patient’s voice before surgery and use text-to-speech synthesis to

reproduce it. However, these approaches fail to capture the patient’s internal self-perception of their voice, o nly the

external recording.

8.2 Inner Voice Approach

Our framework proposes a new protocol:


Pre-surgery: Record the patient’s voice, extract V_raw and V_perceived, compute ΔV


Post-surgery: Record the patient’s new TEP speech

Apply ΔV: Use the pre-surgery ΔV to transform the new speech, restoring not just the vocal timbre but the

patient’s internal perception

This approach preserves vocal identity and self-perception through a traumatic voice loss experience.

8.3 Ethical Considerations

Clinical application requires: – Institutional ethics board approval – Informed consent for voice data storage and

processing – Clear communication about the limitations of voice reconstruction – Patient involvement in defining what

constitutes a successful outcome

The current proof-of-concept is not clinically validated and serves only as a demonstration of the technical

framework.

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